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Latest Medical News from Doctor TV

Adding single type of bacteria to gut microbiome boosted anti-tumor immunity in mice

A bacterium common in the mouse gut microbiome can charge up the immune system to fight cancer cells in the colon, researchers from the University of Pittsburgh School of Medicine report today in the journal Immunity. [...]

Stem cell-based implants successfully secrete insulin in patients with type 1 diabetes

Interim results from a multicenter clinical trial demonstrate insulin secretion from engrafted cells in patients with type 1 diabetes. The safety, tolerability, and efficacy of the implants, which consisted of pancreatic endoderm cells derived from human pluripotent stem cells (PSCs), were tested in 26 patients. While the insulin secreted by the implants did not have clinical effects in the patients, the data are the first reported evidence of meal-regulated insulin secretion by differentiated stem cells in human patients. The results appear December 2 in the journals Cell Stem Cell and Cell Reports Medicine. [...]

Finding could improve in vitro fertilization success rate and lead to non-hormonal, user-friendly contraception

Being able to recapitulate in a dish what human embryos normally do hidden within the womb opens avenues for improving In Vitro Fertilization (IVF) procedures and developing better contraceptives. Hormonal contraceptives have long been used and work for many women. However, they have unpleasant side-effects, and their efficiency decreases if they are not faithfully taken on a daily basis. Also, some women, such as breast cancer survivors, cannot be subjected to hormonal treatments. Using blastoids, which are cellular models of early-stage human embryos, IMBA researcher Dr. Nicolas Rivron and his team discovered molecules that could be candidates for contraceptives or… [...]

The largest ever study of the plasma proteome published

In a study published today in Nature Genetics, scientists at deCODE genetics , a subsidiary of the pharmaceutical company Amgen, demonstrate how measuring the levels of a large number of proteins in plasma at population scale when combined with data on sequence diversity and RNA expression dramatically increases insights into human diseases and other phenotypes. [...]

Tracking the neurons that make us social

Human beings, like most mammals, need social interactions to live and develop. The processes that drive them toward each other require decision making whose brain machinery is largely misunderstood. To decipher this phenomenon, a team from the University of Geneva (UNIGE) has studied the neurobiological mechanisms at stake when two mice come into contact through learning a task. They observed that the motivation to invest in a social interaction is closely linked to the reward system, via the activation of dopaminergic neurons. These results, to be read in the journal Nature Neuroscience, will make it possible to study physiologically the… [...]

Does cancer immunotherapy work differently in men vs. women?

A class of cancer immunotherapy called checkpoint inhibitors has revolutionized cancer treatment. It's a new way to attack the disease by unleashing the immune system. However, not every patient benefits from the treatment, and it can cause severe, sometimes life-threatening, side effects in some. New research shows that one group of patients may be at greater risk. The results, published in JAMA Network Open December 2nd, show that women with advanced melanoma are twice as likely as men to die when treated with the same combination of checkpoint inhibitors. [...]

'Mild cognitive impairment' in older age often disappears, study finds

(HealthDay)—A diagnosis of mild cognitive impairment (MCI) might worry an older adult, who could see it as a stepping stone to dementia. But a new study suggests one does not necessarily lead to the other. [...]

Biden to announce plan to battle Omicron, Delta variants this winter

(HealthDay)—President Joe Biden plans to announce a new round of measures to protect Americans against the spread of coronavirus variants on Thursday. [...]

Pandemic stress, exhaustion weigh on health care workers

(HealthDay)—The pandemic is taking a toll on health care workers' sleep, which can put both their mental health and patient care at risk, researchers warn. [...]

Are pandemic-related stressors increasing young women's vulnerability to STIs?

Researchers at the University of Illinois Chicago have been awarded $2.6 million in research funding from the National Institutes of Health to study how pandemic-related stressors influence sexual behavior and risk of sexually transmitted infections among girls and young women in Kenya. [...]