Diabetes News

  • MicroRNA-708 overexpression suppresses beta-cell proliferation
    (HealthDay)—Researchers have identified a novel mechanism of glucose regulation of β-cell function and growth by repressing stress-induced microRNA-708 (miR-708), according to a study published online Oct. 2 in Diabetes. Read more »
  • Lower brain glucose levels found in people with obesity, type 2 diabetes
    Glucose levels are reduced in the brains of individuals with obesity and type 2 diabetes compared to lean individuals, according to a new Yale study. The finding might explain disordered eating behavior—and even a higher risk of Alzheimer's disease—among obese and diabetic individuals, the researchers said. Read more »
  • Exercise nerve response in type 1 diabetes worsens over time
    A new study finds that late-stage type 1 diabetes mellitus (T1DM) weakens the autonomic reflex that regulates blood pressure during exercise, impairing circulation, nerve function and exercise tolerance. The study is published in the American Journal of Physiology—Heart and Circulatory Physiology. Read more »
  • Clinical evidence synopsis published for T2DM
    (HealthDay)—Adding a sulfonylurea or metformin to insulin is associated with approximately a 1 percent reduction in hemoglobin A1c (HbA1c), and addition of a sulfonylurea (but not metformin) is associated with more hypoglycemic events, according a clinical evidence synopsis published online Oct. 17 in the Journal of the American Medical Association. Read more »
  • Lifestyle, metformin interventions have variable effects
    (HealthDay)—For individuals with impaired glucose regulation, the impact of lifestyle and metformin interventions vary for progression to diabetes mellitus (DM) and likelihood of regression to normal glucose regulation (NGR), according to a study published online Oct. 11 in Diabetes Care. Read more »
  • Diabetes foot care services may help avoid lower limb amputations
    In a Diabetic Medicine study that compared different regions in England, areas that provided 10 key services for diabetes foot care had lower rates of major diabetes-related lower limb amputations. Read more »
  • Venovenous hemodiafiltration improves metformin toxicity
    (HealthDay)—High-volume continuous venovenous hemodiafiltration (CVVH) and resin-sorbent hemoperfusion is effective for eliminating metformin, according to a case study published online Oct. 5 in the Journal of Diabetes Investigation. Read more »
  • On-and-off fasting helps fight obesity
    Up to sixteen weeks of intermittent fasting without otherwise having to count calories helps fight obesity and other metabolic disorders. Such fasting already shows benefits after only six weeks. This is according to a study by Kyoung-Han Kim and Yun Hye Kim in the journal Cell Research. Intermittent fasting in mice helped to kick-start the animals' metabolism and to burn fat by generating body heat. The research team was led by Hoon-Ki Sung of The Hospital for Sick Children in Ontario, Canada. Read more »
  • Diabetes pill might replace injection to control blood sugar
    (HealthDay)— An injectable class of diabetes medication—called glucagon-like peptide-1 or GLP-1—might one day be available in pill form, research suggests. Read more »
  • Skimping on sleep may contribute to gestational diabetes
    The amount of time spent sleeping in the United States has dropped significantly in the past twenty years with almost a quarter of women and 16 percent of men experiencing insufficient sleep. Now, a new study has found that lack of sleep among pregnant women may be a contributing factor to the development of gestational diabetes. Read more »
  • GP referral to Weight Watchers avoided type 2 diabetes in third of patients
    More than a third of patients at risk of developing type 2 diabetes avoided developing the condition after they were referred by their family doctor (GP) to a diabetes prevention programme delivered by the commercial weight management provider, Weight Watchers, finds research published in BMJ Open Diabetes Research & Care. Read more »
  • Healthy lifestyle reduces cardiovascular risk after gestational diabetes, study shows
    A history of gestational diabetes was associated with a modest higher long-term risk of cardiovascular disease in women in a new study, although the absolute rate of cardiovascular disease was low in the study's younger group of predominantly white women and adhering to a healthy lifestyle over time appeared to help mitigate the risk, according to a new article published by JAMA Internal Medicine. Read more »
  • Recognising monogenic diabetes is vital for its management
    Distinguishing monogenic diabetes in the young – that is, a rare type of diabetes caused by a single genetic mutation relatively early in life—from other types of diabetes, is crucial for appropriate therapies, prognosis and family screening, according to research that has been published in the Medical Journal of Australia. Read more »
  • Artificial pancreas performs well in clinical trial
    During more than 60,000 hours of combined use of a novel artificial pancreas system, participants in a 12-week, multi-site clinical trial showed significant improvements in two key measures of well-being in people living with type 1 diabetes. Read more »
  • Liraglutide not tied to higher risk of cardiovascular events
    (HealthDay)—Liraglutide treatment for weight management is not associated with increased risk of cardiovascular events, according to a study published online Sept. 26 in Diabetes, Obesity and Metabolism. Read more »
  • New type of diabetes caused by a genetic mutation
    Scientists from the ULB Center for Diabetes Research and the Erasmus Hospital of the ULB, together with colleagues at the University of Exeter (UK), University of Helsinki (Finland) and Kyoto University (Japan), have identified a new type of diabetes caused by a mutation in the gene RFX6. Read more »
  • Omega-6 fats may help prevent type 2 diabetes
    The risk of developing type 2 diabetes could be significantly reduced by eating a diet rich in omega-6 polyunsaturated fats, a new study suggests. Read more »
  • No causal link between plasma lipids, diabetic retinopathy
    (HealthDay)—There does not seem to be a causal relationship between plasma lipids and diabetic retinopathy (DR), according to a study published in the September issue of Diabetes. Read more »
  • Insulin pumps associated with lower risk of serious complications among young patients with type 1 diabetes
    Compared with insulin injections, insulin pump therapy among young patients with type 1 diabetes was associated with a lower risk of diabetic ketoacidosis and severe hypoglycemia, according to a study published by JAMA. Read more »
  • Where there's type 1 diabetes, celiac disease may follow
    (HealthDay)—Parents of young children with type 1 diabetes need to be on the lookout for symptoms of another autoimmune condition—celiac disease, new research suggests. Read more »
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