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Study suggests threshold for type 2 diabetes diagnosis in women under 50 years should be lowered

New research presented at the Annual Meeting of the European Association for the Study of Diabetes (EASD) in Hamburg, Germany (2–6 October) and published in the journal Diabetes Therapy suggests that the diagnosis threshold for type 2 diabetes (T2D) should be lowered in women aged under 50 years, since natural blood loss through menstruation could be affecting their blood sugar management. The study is by Dr. Adrian Heald, Salford Royal Hospital, UK, and colleagues. [...]

Teen boys with high blood pressure face danger decades later

Teenage boys who have high blood pressure may find themselves on the road to serious heart problems in adulthood. [...]

Making immunotherapy safe for AML

Acute myeloid leukemia (AML), the second most common leukemia in children, is hard to treat and has a five-year survival rate of just 65 to 70%, according to the American Cancer Society. While immunotherapies like monoclonal antibodies or CAR T-cell therapy are effective for certain blood cancers, they have not been possible in AML because of toxicity concerns. It's been hard to find targets on leukemia cells that normal blood stem cells don't share, so immunotherapy runs the risk of harming normal cells. [...]

Stem cell treatment halts MS for some patients

A new study is strengthening the evidence that stem cell transplants can be highly effective for some people with multiple sclerosis—sending the disease into remission for years, and sometimes reversing disability. [...]

New study offers hope for pulmonary fibrosis patients

Using a new recipe for growing blood vessels from living lung tissue in the lab, a University of Virginia School of Engineering and Applied Science research team has developed an analytical tool that could lead to a cure for idiopathic pulmonary fibrosis, or IPF, a lung-destroying disease. [...]

Neural activity associated with motor commands changes depending on context

Standing at a crosswalk, the signal changes from "don't walk," to "walk." You might step out into the street straight away, or you might look both ways before you cross. [...]

True progression or pseudoprogression in glioblastoma patients?

Is it true progression or pseudoprogression in tumor growth? [...]

Prostate cancer can be treated as effectively using fewer and higher doses of radiation therapy, finds phase III trial

People with intermediate risk, localized prostate cancer can be treated as effectively using fewer and higher doses of radiation therapy delivered over five treatment sessions as they can with lower doses delivered over several weeks, a new phase III randomized trial suggests. [...]

An artificial muscle to study Duchenne muscular dystrophy

Duchenne muscular dystrophy (DMD) is the most common muscular dystrophy diagnosed in childhood, with approximately 20,000 new cases reported each year. It is a progressive muscle disorder that results in the loss of muscle function, ultimately leading those affected to lose their independence and experience severe medical issues. The average life expectancy for individuals with DMD is around 30 years. [...]

Atopic dermatitis: Viruses discovered as new therapy option

Up to 15% of children and 5% of adults are affected by the chronic inflammatory skin disease atopic dermatitis. Despite advanced therapy measures, the severe itching and eczema, especially on the elbows or knees, cause great distress to the patients. [...]